Breast Cancer Imaging
Study on the Breast Cancer Imaging Techniques in (Nepalese)Women
The main objective of this review is to do the systematic bibliographic study of past, present and future paradigm of the breast cancer.
There are various multimodal images being used in the clinical setting for breast cancer. The primary objectives will explore and describe various physic related aspects to these imaging modalities. For example, ionising and non-ionising technique, image formation/reconstruction and its tissue characteristics e.t.c. The body of thesis will contain the comparison of images of cancer cells taken by different techniques like CT, MRI, PET, X-ray etc. In these comparisons will point out why any particular image is better than other images to provide more distinct and clear information about cancer cells about cancer non-invasively. Also we can include the advancement of imaging techniques in cancer cell imaging by comparing past, present and future with the help of any law in physics.
The secondary objectives will be focused on I) breast cancer characteristics like demographic, pathologic morphology, WHO criteria, etc. and II) various clinical studies like prognosis, diagnosis, staging etc.
Finally, it will try to evaluate the current breast cancer management in context of Nepal by field visit into some of the hospital in Nepal.
This review will be performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Review and Meta Analyses) guidelines . The following research question will be reviewed.
- Medical imaging: magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), X-ray, ultrasonography (US) and histopathology
- Breast cancer morphology and treatment modalities.
- Diagnostic, grading, treatment monitoring and outcomes assessment.
- State-of-arts algorithm in breast cancer detection, outcome prediction and prognosis
Figure 1 presents the flow diagram for study collection and evaluation. A systematic search will be conducted in the databases of Medline, Embase, and Cochrane Central. The results from all three searches will be combined and verified to ensure exclusion of publications containing the same title, written by the same authors, and published in the same journal. The review will be more focused and detailed on the breast cancer medical imaging (PET, CT, MRI, X-ray, US) related studies however, it will also incorporate few other aspects of breast cancer.
Figure 1. PRISMA flow diagram for study collection.